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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
10.3
Human Site:
S648
Identified Species:
22.67
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S648
I
E
M
E
A
A
S
S
W
Q
V
S
S
F
S
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
T634
D
I
V
D
D
G
T
T
G
N
V
L
S
F
S
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
E651
A
T
H
D
I
E
M
E
A
V
S
S
W
Q
V
Dog
Lupus familis
XP_546733
1387
151432
S632
V
E
A
E
V
A
S
S
W
Q
V
S
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S729
V
E
I
E
V
V
S
S
W
Q
V
S
S
F
S
Rat
Rattus norvegicus
Q62688
1096
122754
N411
P
L
S
H
Y
Y
I
N
A
S
H
N
T
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
H73
I
E
T
V
R
E
G
H
Q
S
E
V
L
Q
S
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Q99
E
C
V
R
E
G
C
Q
S
E
C
L
R
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
C623
N
A
E
K
K
N
R
C
Y
E
M
S
S
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
C723
G
F
P
E
N
M
P
C
W
E
L
P
S
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
26.6
6.6
80
N.A.
73.3
0
N.A.
N.A.
0
20
0
N.A.
20
N.A.
N.A.
20
P-Site Similarity:
100
53.3
13.3
86.6
N.A.
86.6
26.6
N.A.
N.A.
0
20
13.3
N.A.
46.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
10
19
0
0
19
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
10
19
0
0
10
0
0
0
0
% C
% Asp:
10
0
0
19
10
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
37
10
37
10
19
0
10
0
28
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
46
0
% F
% Gly:
10
0
0
0
0
19
10
0
10
0
0
0
0
0
10
% G
% His:
0
0
10
10
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
19
10
10
0
10
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
10
19
10
10
10
% L
% Met:
0
0
10
0
0
10
10
0
0
0
10
0
0
0
10
% M
% Asn:
10
0
0
0
10
10
0
10
0
10
0
10
0
0
0
% N
% Pro:
10
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
28
0
0
0
19
0
% Q
% Arg:
0
0
0
10
10
0
10
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
10
0
0
0
28
28
10
19
10
46
55
0
46
% S
% Thr:
0
10
10
0
0
0
10
10
0
0
0
0
10
0
0
% T
% Val:
19
0
19
10
19
10
0
0
0
10
37
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
37
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _